OR5AU1

Across TCGA patient cohorts, OR5AU1 mutation is significantly associated with the RNA expression of many other genes, with 554 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AU1-associated genes across cancer lineages are RNU6-18P, TRPC7-AS2, and RNU6-391P. Each is linked with OR5AU1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AU1-to-partner and partner-to-OR5AU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-18P grouped by OR5AU1-low versus OR5AU1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AU1→partner) and Y-score (partner→OR5AU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-18P →	+0.209	+4.554	.005	.009	3	2
LUAD	TRPC7-AS2 →	+0.066	+4.888	<.001	.005	3	2
BRCA	RNU6-391P →	+0.331	+7.731	<.001	.009	3	2
BLCA	RNU6-212P →	+0.411	+4.533	.001	.005	3	2
BLCA	MIR629 →	+0.335	+5.147	<.001	.003	3	2
LUSC	MIR8082 →	+0.330	+4.578	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 554 associations by consensus.

RNU6-18P by OR5AU1 expression — LUAD

Explore this box plot interactively →