OR5AU1

Across TCGA pan-cancer cohorts, OR5AU1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated OR5AU1 data layer compared with 6 for mutation status.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher OR5AU1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR5AU1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LIHC show a favorable association.

READ, SKCM, and BRCA are the cancer types where OR5AU1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	III,IV	0.190	0.767	<.001	63	view →
SKCM	OS	Tertile	II,III,IV	0.239	0.434	.015	19	view →
BRCA	OS	Tertile	III,IV	0.714	0.858	.009	18	view →
SARC	DFS	Tertile	All	0.368	0.622	.006	18	view →
ACC	OS	Tertile	III,IV	0.357	0.751	.042	9	view →
THCA	DFS	Tertile	All	0.478	0.839	.013	9	view →
LGG	DFS	Tertile	All	0.637	0.752	.027	9	view →
UCEC	OS	Median	III,IV	0.879	0.786	.031	6	view →
LIHC	DFS	Tertile	All	0.626	0.279	.047	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

OR5AU1–READ (DFS)

Open the READ breakdown →