OR5A2

Across TCGA patient cohorts, OR5A2 mutation is significantly associated with the RNA expression of many other genes, with 845 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5A2-associated genes across cancer lineages are MIR4497, SUMO2P10, and DIP2C. Each is linked with OR5A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5A2-to-partner and partner-to-OR5A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4497 grouped by OR5A2-low versus OR5A2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5A2→partner) and Y-score (partner→OR5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR4497 →	+0.488	+5.070	<.001	.008	3	3
SKCM	SUMO2P10 →	+0.123	+2.942	.003	.001	3	3
UCEC	DIP2C →	+0.759	+3.346	.004	.005	3	2
LUAD	GOLGA6L16P →	+0.034	+5.155	<.001	.002	3	2
LUAD	RNU6-23P →	+0.236	+4.612	<.001	.006	3	2
LUAD	TEX36-AS1 →	+0.047	+4.730	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 845 associations by consensus.

MIR4497 by OR5A2 expression — BRCA

Explore this box plot interactively →