OR56B4

Across TCGA patient cohorts, OR56B4 mutation is significantly associated with the RNA expression of many other genes, with 3,438 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR56B4-associated genes across cancer lineages are VN1R54P, HNRNPUL2-BSCL2, and SNORA71B. Each is linked with OR56B4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR56B4-to-partner and partner-to-OR56B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R54P grouped by OR56B4-low versus OR56B4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56B4→partner) and Y-score (partner→OR56B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VN1R54P →	+0.495	+1.969	.001	.007	3	3
SKCM	HNRNPUL2-BSCL2 →	+0.415	+2.925	<.001	.001	3	2
SKCM	SNORA71B →	+0.641	+2.241	.003	.006	3	2
SKCM	MRPL42P6 →	+0.052	+2.858	<.001	.009	3	2
SKCM	ARHGEF38-IT1 →	+0.057	+2.454	<.001	.004	3	2
HNSC	KRTAP19-8 →	+0.264	+3.449	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

VN1R54P by OR56B4 expression — UCEC

Explore this box plot interactively →