Q-omics provides the consensus-scored VN1R54P profile across patient tissues and cancer cell-line models. VN1R54P expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, VN1R54P is differentially expressed in 5, with the highest sampling consensus in HNSC. Additionally, VN1R54P RNA expression shows 9,106 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, HNSC, and THYM as cancer lineages where VN1R54P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for VN1R54P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes VN1R54P survival associations across molecular data types. VN1R54P RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible VN1R54P RNA expression–survival associations across cancer types. High VN1R54P expression shows unfavorable associations in COAD, READ, KIRC, STAD, LIHC and BRCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for VN1R54P RNA expression.
This table summarizes VN1R54P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for VN1R54P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. VN1R54P shows higher tumor expression in HNSC, LUAD, PRAD, UCEC and LUSC. The HNSC box plot shows higher VN1R54P RNA expression in tumor versus normal tissue (log2 FC = +0.125, t-test p < 0.001).
This table shows molecular features associated with VN1R54P in patient tissues and cancer cell lines. In patient samples, VN1R54P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
