OR56B4

Across TCGA pan-cancer cohorts, OR56B4 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated OR56B4 data layer compared with 3 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher OR56B4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated OR56B4 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

UCS, LGG, and LIHC are the cancer types where OR56B4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	III,IV	0.700	0.185	.005	40	view →
LGG	OS	Median	All	0.729	0.854	<.001	35	view →
LIHC	OS	Median	II,III,IV	0.544	0.791	<.001	30	view →
ACC	DFS	Quartile	II,III,IV	0.405	0.704	.014	20	view →
SKCM	DFS	Median	IV	0.187	0.763	.006	15	view →
BRCA	DFS	Median	III,IV	0.857	0.736	.005	12	view →
TGCT	DFS	Quartile	All	0.656	0.928	.013	12	view →
ESCA	DFS	Median	II,III,IV	1.000	0.452	.023	9	view →
DLBC	DFS	Quartile	All	0.466	0.939	.013	9	view →
CESC	DFS	Tertile	II,III,IV	0.329	0.579	.029	8	view →
LUAD	DFS	Quartile	All	0.790	0.598	.011	7	view →
SARC	OS	Tertile	All	0.654	0.848	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

OR56B4–UCS (OS)

Open the UCS breakdown →