OR52W1

Across TCGA patient cohorts, OR52W1 mutation is significantly associated with the RNA expression of many other genes, with 286 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52W1-associated genes across cancer lineages are RNU1-6P, RN7SL186P, and EI24. Each is linked with OR52W1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52W1-to-partner and partner-to-OR52W1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-6P grouped by OR52W1-low versus OR52W1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52W1→partner) and Y-score (partner→OR52W1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU1-6P →	+0.437	+6.814	<.001	<.001	3	1
BLCA	RN7SL186P →	+0.232	+5.038	<.001	.009	3	1
UCEC	EI24 →	+0.549	+3.212	.008	.009	3	1
UCEC	SPAG17 →	-0.961	-3.459	.004	.005	3	1
UCEC	AP3S2 →	+0.381	+3.223	.008	.009	3	1
UCEC	CPAMD8 →	-1.384	-3.437	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 286 associations by consensus.

RNU1-6P by OR52W1 expression — BLCA

Explore this box plot interactively →