OR52N5

Across TCGA patient cohorts, OR52N5 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52N5-associated genes across cancer lineages are ACC1, PDCD4, and ERK2. Each is linked with OR52N5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52N5-to-partner and partner-to-OR52N5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by OR52N5-low versus OR52N5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N5→partner) and Y-score (partner→OR52N5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.361	+1.700	.019	.044	3	2
UCEC	PDCD4 →	-0.744	-3.321	<.001	.009	3	2
SKCM	ERK2 →	+0.263	+3.169	.022	.019	3	2
LUSC	S6_pS235_S236 →	+0.451	+3.009	.036	.019	3	1
LUSC	S6_pS240_S244 →	+0.626	+3.009	.019	.019	3	1
UCEC	eEF2 →	+0.392	+1.700	.009	.044	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

ACC1 by OR52N5 expression — UCEC

Explore this box plot interactively →