OR52N5

Across TCGA cell cohorts, OR52N5 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52N5-associated genes across cancer lineages are DEFB132, PRAMEF12, and CST8. Each is linked with OR52N5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52N5-to-partner and partner-to-OR52N5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB132 grouped by OR52N5-low versus OR52N5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N5→partner) and Y-score (partner→OR52N5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DEFB132 →	+0.099	+5.415	<.001	.004	3	2
LARGE_INTESTINE	PRAMEF12 →	+0.099	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CST8 →	+0.029	+5.415	<.001	.004	3	1
LARGE_INTESTINE	USP29 →	+0.012	+5.415	<.001	.004	3	1
LARGE_INTESTINE	EDDM3A →	+0.380	+4.977	<.001	.007	3	1
LARGE_INTESTINE	OR5P3 →	+0.131	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

DEFB132 by OR52N5 expression — LARGE_INTESTINE

Explore this box plot interactively →