Across TCGA patient cohorts, OR52E6 mutation is significantly associated with the RNA expression of many other genes, with 1,654 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52E6-associated genes across cancer lineages are AOC1, DOC2B, and RNA5SP411. Each is linked with OR52E6 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52E6-to-partner and partner-to-OR52E6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52E6→partner) and Y-score (partner→OR52E6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AOC1 →	-1.925	-3.000	.002	.001	3	3
UCEC	DOC2B →	-1.064	-2.321	.001	.006	3	2
UCEC	RNA5SP411 →	+1.002	+2.071	<.001	.003	3	2
SKCM	TTTY15 →	+0.909	+2.077	<.001	<.001	3	2
SKCM	TCEA1P4 →	+0.157	+1.701	.008	.006	3	2
UCEC	CWC27 →	+0.474	+3.235	.009	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,654 associations by consensus.

Exploration

OR52E6 survival (RNA) · tumor vs normal (RNA) · all OR52E6 data types