Across TCGA pan-cancer cohorts, OR52E6 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR52E6’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where OR52E6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR52E6 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

BRCA, LIHC, and STAD are the cancer types where OR52E6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR52E6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.056	.003	4	view →
LIHC	All	All	+0.041	.002	4	view →
STAD	All	All	+0.048	.038	1	view →
LUSC	All	All	+0.026	.033	1	view →
KIRC	Male	II,III,IV	−0.010	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: OR52E6 RNA expression & survival · all OR52E6 data types