OR52E4

Across TCGA patient cohorts, OR52E4 mutation is significantly associated with the RNA expression of many other genes, with 738 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR52E4-associated genes across cancer lineages are RNU6-752P, OR51V1, and LINC01162. Each is linked with OR52E4 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR52E4-to-partner and partner-to-OR52E4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-752P grouped by OR52E4-low versus OR52E4-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52E4→partner) and Y-score (partner→OR52E4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-752P →	+0.453	+6.147	<.001	.002	3	4
SCLC	OR51V1 →	+0.074	+4.624	<.001	.006	3	3
CESC	LINC01162 →	+0.337	+4.669	<.001	.007	3	3
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	3
CESC	DNAJB8-AS1 →	+0.050	+4.760	<.001	.003	3	3
SKCM	CAMTA1-IT1 →	+0.147	+1.660	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 738 associations by consensus.

RNU6-752P by OR52E4 expression — BLCA

Explore this box plot interactively →