OR52E4

Across TCGA pan-cancer cohorts, OR52E4 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated OR52E4 data layer compared with 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher OR52E4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR52E4 expression acts as an unfavorable survival marker.

UCEC, ESCA, and KIRC are the cancer types where OR52E4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.795	0.902	.001	60	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	54	view →
KIRC	DFS	Tertile	IV	0.149	0.648	<.001	42	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	36	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	36	view →
LIHC	OS	Tertile	II,III,IV	0.476	0.721	.019	21	view →
UCS	DFS	Tertile	IV	0.321	0.805	.012	18	view →
LGG	OS	Tertile	All	0.610	0.908	.004	18	view →
SCLC	DFS	Tertile	All	0.307	0.651	.009	12	view →
STAD	OS	Tertile	III,IV	0.152	0.507	.025	9	view →
SKCM	DFS	Tertile	III,IV	0.332	0.617	.021	9	view →
BLCA	OS	Tertile	IV	0.141	0.573	.034	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

OR52E4–UCEC (DFS)

Open the UCEC breakdown →