Across TCGA pan-cancer cohorts, OR52E4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR52E4’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where OR52E4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR52E4 is over-expressed in tumor.
BRCA, LIHC, and LUAD are the cancer types where OR52E4 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR52E4 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.