OR51Q1

Across TCGA patient cohorts, OR51Q1 mutation is significantly associated with the RNA expression of many other genes, with 2,941 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51Q1-associated genes across cancer lineages are SKA1, SKA3, and CDT1. Each is linked with OR51Q1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51Q1-to-partner and partner-to-OR51Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKA1 grouped by OR51Q1-low versus OR51Q1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51Q1→partner) and Y-score (partner→OR51Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA1 →	+0.717	+2.180	<.001	.002	3	3
UCEC	SKA3 →	+0.629	+2.191	.001	.002	3	3
UCEC	CDT1 →	+0.913	+2.695	<.001	<.001	3	3
UCEC	LMNB2 →	+0.670	+3.753	<.001	<.001	3	3
LUAD	RAD51 →	+0.689	+3.357	.002	.005	3	3
UCEC	GTSE1 →	+0.807	+2.234	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,941 associations by consensus.

SKA1 by OR51Q1 expression — UCEC

Explore this box plot interactively →