OR51Q1

Across TCGA pan-cancer cohorts, OR51Q1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated OR51Q1 data layer compared with 2 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher OR51Q1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated OR51Q1 expression acts as an unfavorable survival marker, although some lineages such as OV and UCS show a favorable association.

OV, UCS, and THCA are the cancer types where OR51Q1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	IV	0.576	0.268	<.001	92	view →
UCS	OS	Tertile	II,III,IV	1.000	0.524	.011	60	view →
THCA	DFS	Tertile	III,IV	0.503	0.877	<.001	54	view →
KICH	OS	Tertile	II,III,IV	0.653	0.967	<.001	45	view →
READ	OS	Tertile	IV	0.334	0.918	<.001	36	view →
LUAD	DFS	Tertile	IV	0.418	0.745	.043	36	view →
LGG	OS	Tertile	All	0.649	0.408	.001	30	view →
KIRP	DFS	Tertile	III,IV	0.826	0.286	.018	21	view →
THYM	OS	Tertile	All	0.736	0.945	.008	18	view →
TGCT	DFS	Quartile	III,IV	0.505	1.000	.031	14	view →
COAD	OS	Tertile	III,IV	0.193	0.558	.025	12	view →
ACC	DFS	Tertile	III,IV	0.057	0.457	.040	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

OR51Q1–OV (OS)

Open the OV breakdown →