OR51B5

Across TCGA cell cohorts, OR51B5 mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51B5-associated genes across cancer lineages are GSK2276186C, 776928, and alpha-lipoic acid. Each is linked with OR51B5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51B5-to-partner and partner-to-OR51B5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK2276186C grouped by OR51B5-low versus OR51B5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B5→partner) and Y-score (partner→OR51B5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2276186C →	+0.456	+2.871	.038	.021	3	1
LARGE_INTESTINE	776928 →	+0.620	+2.871	.039	.021	3	1
LARGE_INTESTINE	alpha-lipoic acid →	+0.342	+2.684	.017	.035	3	1
LARGE_INTESTINE	Dactinomycin →	+0.652	+2.649	.022	.046	2	1
LARGE_INTESTINE	GSK429286A →	+0.327	+2.874	.027	.021	2	1
LARGE_INTESTINE	Dinaciclib →	+0.517	+2.868	.034	.022	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

GSK2276186C by OR51B5 expression — LARGE_INTESTINE

Explore this box plot interactively →