OR51B5

Across TCGA pan-cancer cohorts, OR51B5 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated OR51B5 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher OR51B5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR51B5 expression acts as an unfavorable survival marker, although some lineages such as UCS and MESO show a favorable association.

UVM, ACC, and COAD are the cancer types where OR51B5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.401	0.788	<.001	114	view →
ACC	DFS	Tertile	All	0.322	0.783	<.001	48	view →
COAD	DFS	Quartile	All	0.260	0.636	.002	43	view →
UCS	DFS	Tertile	II,III,IV	0.574	0.118	.001	42	view →
MESO	OS	Median	All	0.497	0.312	.008	25	view →
LUAD	DFS	Median	IV	0.512	0.936	.009	24	view →
LGG	OS	Median	All	0.838	0.927	<.001	22	view →
KIRC	DFS	Quartile	III,IV	0.344	0.556	.012	20	view →
READ	DFS	Tertile	IV	0.112	0.811	.008	18	view →
BLCA	DFS	Quartile	All	0.414	0.671	.004	16	view →
BRCA	OS	Tertile	III,IV	0.303	0.720	.006	15	view →
PAAD	OS	Tertile	All	0.273	0.492	.019	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

OR51B5–UVM (DFS)

Open the UVM breakdown →