OR51B5

Across TCGA pan-cancer cohorts, OR51B5 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR51B5’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OR51B5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR51B5 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

HNSC, KICH, and LIHC are the cancer types where OR51B5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR51B5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.664	.010	8	view →
KICH	All	II,III,IV	−0.150	.001	6	view →
LIHC	All	All	+0.216	.007	4	view →
BRCA	All	III,IV	−0.038	.036	2	view →
LUSC	All	III,IV	−0.053	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

OR51B5–HNSC

Open the HNSC breakdown →