OR51A7

Across TCGA patient cohorts, OR51A7 mutation is significantly associated with the RNA expression of many other genes, with 2,078 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51A7-associated genes across cancer lineages are GPR3, RNU6-492P, and RNU11. Each is linked with OR51A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51A7-to-partner and partner-to-OR51A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR3 grouped by OR51A7-low versus OR51A7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51A7→partner) and Y-score (partner→OR51A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GPR3 →	+0.423	+1.945	.009	.002	3	3
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	2
UCEC	RNU11 →	+0.759	+2.299	<.001	.002	3	2
UCEC	FRG1HP →	+0.487	+2.280	.001	.001	3	2
UCEC	CCT5 →	+0.519	+3.754	.005	<.001	3	2
UCEC	CENPU →	+0.600	+1.880	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,078 associations by consensus.

GPR3 by OR51A7 expression — SKCM

Explore this box plot interactively →