OR4S1

Across TCGA cell cohorts, OR4S1 RNA expression is significantly associated with the mutation status of many other genes, with 58 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR4S1-associated genes across cancer lineages are AMN1, USP43, and PLXNB2. Each is linked with OR4S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4S1-to-partner and partner-to-OR4S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMN1 grouped by OR4S1-low versus OR4S1-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4S1→partner) and Y-score (partner→OR4S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	AMN1 →	+4.643	+0.063	.008	<.001	3	1
LUNG_NSCLC_LUSC	USP43 →	+4.643	+0.063	.008	<.001	3	1
LUNG_NSCLC_LUSC	PLXNB2 →	+4.643	+0.063	.008	<.001	3	1
LUNG_NSCLC_LUSC	RBM12 →	+4.643	+0.063	.008	<.001	3	1
LUNG_NSCLC_LUSC	LPCAT3 →	+4.643	+0.063	.008	<.001	3	1
LUNG_SCLC	PROM1 →	+5.643	+0.026	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

AMN1 by OR4S1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →