OR4K14

Across TCGA patient cohorts, OR4K14 mutation is significantly associated with the RNA expression of many other genes, with 773 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR4K14-associated genes across cancer lineages are TAF9, SNRPGP8, and RNU7-90P. Each is linked with OR4K14 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4K14-to-partner and partner-to-OR4K14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by OR4K14-low versus OR4K14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K14→partner) and Y-score (partner→OR4K14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF9 →	+0.758	+3.343	<.001	.005	3	3
UCEC	SNRPGP8 →	+0.224	+3.937	<.001	<.001	3	2
UCEC	RNU7-90P →	+0.353	+3.186	<.001	.006	3	2
BRCA	GRAMD4P5 →	+0.094	+4.721	<.001	.007	3	2
LUSC	KIAA1191 →	+0.403	+3.629	<.001	.001	3	2
SKCM	SAR1B →	+0.378	+2.372	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 773 associations by consensus.

TAF9 by OR4K14 expression — UCEC

Explore this box plot interactively →