OR4K14

Across TCGA pan-cancer cohorts, OR4K14 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated OR4K14 data layer compared with 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR4K14 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR4K14 expression acts as an unfavorable survival marker.

COAD, KICH, and ACC are the cancer types where OR4K14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.347	0.871	<.001	162	view →
KICH	DFS	Tertile	All	0.043	0.971	<.001	99	view →
ACC	DFS	Tertile	All	0.046	0.753	<.001	90	view →
SKCM	OS	Tertile	All	0.153	0.781	<.001	54	view →
UCEC	OS	Tertile	III,IV	0.650	0.841	.011	42	view →
LIHC	OS	Tertile	II,III,IV	0.118	0.716	.003	36	view →
BLCA	DFS	Tertile	IV	0.126	0.479	.007	36	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	28	view →
PRAD	OS	Tertile	All	0.962	0.996	<.001	12	view →
HNSC	OS	Tertile	IV	0.415	0.648	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

OR4K14–COAD (OS)

Open the COAD breakdown →