OR4K14

Across TCGA patient cohorts, OR4K14 mutation is significantly associated with the immune_cell of many other genes, with 10 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR4K14-associated genes across cancer lineages are Eosinophils, CD4+ Tem, and CMP. Each is linked with OR4K14 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4K14-to-partner and partner-to-OR4K14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by OR4K14-low versus OR4K14-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K14→partner) and Y-score (partner→OR4K14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Eosinophils →	+0.024	+2.103	<.001	.002	3	3
STAD	CD4+ Tem →	+0.045	+4.450	<.001	.019	3	3
LUSC	CMP →	+0.010	+1.900	.036	.006	3	2
LUSC	Erythrocytes →	+0.016	+1.700	.011	.045	3	2
SKCM	CLP →	+0.055	+1.171	.030	.035	3	1
SKCM	Endothelial cells →	-0.027	-1.974	.029	.029	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Eosinophils by OR4K14 expression — LUSC

Explore this box plot interactively →