Across TCGA cell cohorts, OR4A5 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4A5-associated genes across cancer lineages are BPIFA2, OBP2A, and MPC1L. Each is linked with OR4A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4A5-to-partner and partner-to-OR4A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A5→partner) and Y-score (partner→OR4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	BPIFA2 →	+0.020	+4.807	<.001	.006	3	1
STOMACH	OBP2A →	+0.345	+4.432	<.001	.003	3	1
STOMACH	MPC1L →	+0.204	+4.794	<.001	.001	3	1
LARGE_INTESTINE	CDX4 →	+0.007	+3.217	.001	.006	3	1
LARGE_INTESTINE	OR14K1 →	+0.058	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR10D3 →	+0.007	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

OR4A5 survival (RNA) · tumor vs normal (RNA) · all OR4A5 data types