Across TCGA pan-cancer cohorts, OR4A5 RNA is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR4A5 data layer compared with 5 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher OR4A5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR4A5 expression acts as an unfavorable survival marker.

KIRC, BRCA, and STAD are the cancer types where OR4A5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.153	0.630	.002	54	view →
BRCA	OS	Tertile	III,IV	0.211	0.833	.001	36	view →
STAD	DFS	Tertile	All	0.305	0.716	.018	27	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: OR4A5 tumor-vs-normal RNA expression · all OR4A5 data types