OR4A47

Across TCGA patient cohorts, OR4A47 mutation is significantly associated with the RNA expression of many other genes, with 2,306 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4A47-associated genes across cancer lineages are ACTR5, ARRDC1-AS1, and SPINDOC. Each is linked with OR4A47 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4A47-to-partner and partner-to-OR4A47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTR5 grouped by OR4A47-low versus OR4A47-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A47→partner) and Y-score (partner→OR4A47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACTR5 →	+0.376	+3.906	.005	<.001	3	3
UCEC	ARRDC1-AS1 →	+0.556	+3.343	<.001	.005	3	3
UCEC	SPINDOC →	+0.476	+2.807	.007	.003	3	3
SKCM	WDR74 →	+0.320	+1.953	.001	<.001	3	3
UCEC	GSS →	+0.420	+3.202	.002	.009	3	2
UCEC	SLC7A6OS →	+0.513	+3.939	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,306 associations by consensus.

ACTR5 by OR4A47 expression — UCEC

Explore this box plot interactively →