Across TCGA patient cohorts, OR2W5 mutation is significantly associated with the RNA expression of many other genes, with 3,043 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2W5-associated genes across cancer lineages are BCCIP, DGUOK, and TOMM70. Each is linked with OR2W5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2W5-to-partner and partner-to-OR2W5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2W5→partner) and Y-score (partner→OR2W5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BCCIP →	+0.424	+3.859	.001	<.001	3	3
UCEC	DGUOK →	+0.348	+2.332	.002	<.001	3	3
LUSC	TOMM70 →	+0.334	+1.937	.007	.003	3	3
UCEC	SNF8 →	+0.376	+4.555	.001	<.001	3	3
UCEC	SKA3 →	+0.659	+2.343	<.001	<.001	3	3
UCEC	CCDC43 →	+0.487	+2.354	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,043 associations by consensus.

Exploration

OR2W5 survival (RNA) · tumor vs normal (RNA) · all OR2W5 data types