OR2W3

Across TCGA patient cohorts, OR2W3 mutation is significantly associated with the RNA expression of many other genes, with 2,058 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR2W3-associated genes across cancer lineages are SVIP, LINC01952, and MRPS15. Each is linked with OR2W3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2W3-to-partner and partner-to-OR2W3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SVIP grouped by OR2W3-low versus OR2W3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2W3→partner) and Y-score (partner→OR2W3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SVIP →	+0.800	+3.343	<.001	.005	3	3
UCEC	LINC01952 →	+0.558	+3.500	<.001	.002	3	3
LUAD	MRPS15 →	+0.281	+1.970	.006	.002	3	3
SKCM	SEMA4F →	+0.526	+2.188	.003	.001	3	3
SKCM	OAZ3 →	+0.298	+2.333	<.001	<.001	3	3
LUSC	MRPS25 →	+0.397	+2.330	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,058 associations by consensus.

SVIP by OR2W3 expression — UCEC

Explore this box plot interactively →