OR2T8

Across TCGA patient cohorts, OR2T8 mutation is significantly associated with the RNA expression of many other genes, with 583 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR2T8-associated genes across cancer lineages are DHRS11, RNU6-207P, and RNU6ATAC26P. Each is linked with OR2T8 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T8-to-partner and partner-to-OR2T8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DHRS11 grouped by OR2T8-low versus OR2T8-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T8→partner) and Y-score (partner→OR2T8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DHRS11 →	+0.591	+3.372	.002	.004	3	2
LUAD	RNU6-207P →	+0.475	+4.021	<.001	<.001	3	2
LUAD	RNU6ATAC26P →	+0.285	+2.679	.003	.007	3	2
LUAD	SPATA17-AS1 →	+0.261	+3.213	.002	.002	3	2
STAD	RN7SKP278 →	+0.105	+4.798	.008	.006	3	2
STAD	MIR6885 →	+0.527	+4.691	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 583 associations by consensus.

DHRS11 by OR2T8 expression — SKCM

Explore this box plot interactively →