OR2T8

Across TCGA pan-cancer cohorts, OR2T8 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated OR2T8 data layer compared with 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR2T8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR2T8 expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

COAD, UCEC, and BRCA are the cancer types where OR2T8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.675	0.854	<.001	134	view →
UCEC	OS	Quartile	All	0.511	0.725	<.001	58	view →
BRCA	OS	Tertile	III,IV	0.924	0.743	<.001	33	view →
UCS	DFS	Tertile	II,III,IV	0.571	0.166	.007	28	view →
OV	OS	Quartile	IV	0.559	0.866	<.001	26	view →
LUSC	DFS	Tertile	II,III,IV	0.491	0.796	.006	24	view →
MESO	OS	Median	All	0.728	0.294	.004	24	view →
LUAD	OS	Tertile	II,III,IV	0.572	0.776	.028	12	view →
PCPG	DFS	Tertile	All	0.835	0.965	.011	9	view →
PAAD	DFS	Tertile	All	0.478	0.329	.048	6	view →
SARC	DFS	Median	All	0.446	0.254	.021	6	view →
STAD	DFS	Tertile	III,IV	0.751	0.322	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

OR2T8–COAD (OS)

Open the COAD breakdown →