OR2T8

Across TCGA cell cohorts, OR2T8 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,781 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR2T8-associated GO terms across cancer lineages are Positive regulation of protein localization to mitochondrion, SRP-dependent cotranslational protein targeting to membrane, and Intrinsic apoptotic signaling pathway by p53 class mediator. Each is linked with OR2T8 in more than 5 cancer types. Because this analysis shows association rather than direction, both OR2T8-to-partner and partner-to-OR2T8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to mitochondrion grouped by OR2T8-low versus OR2T8-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T8→partner) and Y-score (partner→OR2T8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of protein localization to mitochondrion →	+0.071	+0.308	<.001	<.001	3	6
SOFT_TISSUE	SRP-dependent cotranslational protein targeting to membrane →	+0.071	+0.335	.002	.007	3	5
SOFT_TISSUE	Intrinsic apoptotic signaling pathway by p53 class mediator →	+0.050	+0.333	.007	.008	3	4
SOFT_TISSUE	Regulation of transmembrane receptor protein serine/threonine kinase signaling pathway →	+0.047	+0.293	<.001	.002	3	4
SOFT_TISSUE	Regulation of transforming growth factor beta receptor signaling pathway →	+0.035	+0.224	.003	.001	3	4
SOFT_TISSUE	Regulation of cellular response to transforming growth factor beta stimulus →	+0.032	+0.196	.006	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,781 associations by consensus.

Positive regulation of protein localization to mitochondrion by OR2T8 expression — BLOOD_Leukemia

Explore this box plot interactively →