OR2T4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2T4 mutation is significantly associated with the RNA expression of many other genes, with 2,721 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR2T4-associated genes across cancer lineages are MIR6803, RNU6-183P, and TPRX2P. Each is linked with OR2T4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2T4-to-partner and partner-to-OR2T4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T4→partner) and Y-score (partner→OR2T4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6803 →+0.172+4.671<.001.00233
LGGRNU6-183P →+0.427+7.155<.001<.00133
LGGTPRX2P →+0.057+5.148<.001.00733
LUSCPNO1 →+0.403+2.842<.001.00133
LUADTSFM →+0.383+2.611.003.00533
LUADCOG6 →+0.390+1.789.001.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,721 associations by consensus.

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