Across TCGA pan-cancer cohorts, OR2T4 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated OR2T4 data layer compared with 5 for mutation status.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher OR2T4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR2T4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and PAAD show a favorable association.
BLCA, LUAD, and KIRC are the cancer types where OR2T4 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.