Across TCGA patient cohorts, OR2T2 mutation is significantly associated with the RNA expression of many other genes, with 561 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR2T2-associated genes across cancer lineages are ATF4P4, OR6C4, and RPL14P6. Each is linked with OR2T2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2T2-to-partner and partner-to-OR2T2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T2→partner) and Y-score (partner→OR2T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ATF4P4 →	+0.147	+2.201	.002	.001	3	3
LUAD	OR6C4 →	+0.029	+4.523	<.001	.004	3	2
LUAD	RPL14P6 →	+0.251	+3.878	<.001	.001	3	2
LUAD	OR51A8P →	+0.069	+3.307	.006	.007	3	2
LUAD	LINC02438 →	+0.832	+3.061	<.001	.005	3	2
LUAD	G2E3-AS1 →	+0.801	+3.178	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 561 associations by consensus.

Exploration

OR2T2 survival (RNA) · tumor vs normal (RNA) · all OR2T2 data types