Across TCGA cell cohorts, OR2T10 mutation is significantly associated with the mutation status of many other genes, with 158 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2T10-associated genes across cancer lineages are WDR25, LPA, and OR10T2. Each is linked with OR2T10 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T10-to-partner and partner-to-OR2T10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T10→partner) and Y-score (partner→OR2T10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	WDR25 →	+5.824	+5.824	.002	.002	1	2
LUNG_NSCLC_LUAD	LPA →	+2.799	+3.791	<.001	<.001	1	2
LUNG_SCLC	OR10T2 →	+4.066	+5.022	.001	.001	1	2
LUNG_NSCLC_LUAD	IQGAP3 →	+2.340	+3.430	.002	.002	1	2
LUNG_SCLC	SDK2 →	+4.066	+5.022	.001	.001	1	2
SKIN	FAM83C →	+4.239	+5.053	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 158 associations by consensus.

Exploration

OR2T10 survival (RNA) · tumor vs normal (RNA) · all OR2T10 data types