OR2M4

Across TCGA patient cohorts, OR2M4 mutation is significantly associated with the RNA expression of many other genes, with 1,041 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR2M4-associated genes across cancer lineages are RNA5SP213, VN1R35P, and EP300-AS1. Each is linked with OR2M4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2M4-to-partner and partner-to-OR2M4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP213 grouped by OR2M4-low versus OR2M4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M4→partner) and Y-score (partner→OR2M4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP213 →	+0.177	+3.104	<.001	.006	3	3
SKCM	VN1R35P →	+0.091	+2.373	<.001	<.001	3	3
SKCM	EP300-AS1 →	+0.424	+2.153	.001	.009	3	3
HNSC	TRGJP2 →	+0.725	+3.871	.002	.004	3	2
HNSC	IGHD6-19 →	+1.525	+3.867	<.001	.002	3	2
UCEC	ERMAP →	-0.556	-3.646	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,041 associations by consensus.

RNA5SP213 by OR2M4 expression — LUSC

Explore this box plot interactively →