Across TCGA cell cohorts, OR2L5 mutation is significantly associated with the mutation status of many other genes, with 308 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible OR2L5-associated genes across cancer lineages are BEND4, EHMT2, and E2F2. Each is linked with OR2L5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2L5-to-partner and partner-to-OR2L5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2L5→partner) and Y-score (partner→OR2L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	BEND4 →	+5.339	+4.772	.004	.004	1	3
BREAST	EHMT2 →	+3.121	+4.339	.005	.005	1	2
BREAST	E2F2 →	+4.857	+4.297	.009	.009	1	2
BREAST	KLHL36 →	+4.857	+4.297	.009	.009	1	2
SKIN	FGG →	+4.239	+5.053	.007	.007	1	2
SKIN	ZNF354C →	+4.824	+5.392	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 308 associations by consensus.

Exploration

OR2L5 survival (RNA) · tumor vs normal (RNA) · all OR2L5 data types