Across TCGA pan-cancer cohorts, OR2L5 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR2L5’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OR2L5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR2L5 is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

HNSC and UCEC are the cancer types where OR2L5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR2L5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.034	.009	3	view →
UCEC	All	All	−0.063	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: OR2L5 RNA expression & survival · all OR2L5 data types