OR2G2

Across TCGA patient cohorts, OR2G2 mutation is significantly associated with the RNA expression of many other genes, with 1,325 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2G2-associated genes across cancer lineages are DUSP14, MEAK7, and ZIK1P1. Each is linked with OR2G2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2G2-to-partner and partner-to-OR2G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUSP14 grouped by OR2G2-low versus OR2G2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2G2→partner) and Y-score (partner→OR2G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DUSP14 →	+0.451	+2.247	.001	.001	3	3
LUAD	MEAK7 →	+0.472	+2.505	<.001	.009	3	3
LUAD	ZIK1P1 →	+0.013	+2.312	<.001	.005	3	3
UCEC	HS1BP3 →	+0.345	+2.828	.005	.001	3	3
SKCM	RPP30 →	+0.318	+2.151	.001	.002	3	3
UCEC	PLEKHJ1 →	+0.613	+3.732	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,325 associations by consensus.

DUSP14 by OR2G2 expression — SKCM

Explore this box plot interactively →