OR2C1

Across TCGA cell cohorts, OR2C1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2C1-associated genes across cancer lineages are OCM2, OR56A5, and IQCF3. Each is linked with OR2C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2C1-to-partner and partner-to-OR2C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OCM2 grouped by OR2C1-low versus OR2C1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2C1→partner) and Y-score (partner→OR2C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OCM2 →	+0.045	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR56A5 →	+0.111	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.045	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.045	+4.887	<.001	.009	3	1
SKIN	OR5K2 →	+0.066	+3.747	<.001	.008	3	1
LUNG_SCLC	OR5M1 →	+0.015	+5.029	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OCM2 by OR2C1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →