OR2C1

Across TCGA cell cohorts, OR2C1 mutation is significantly associated with the mutation status of many other genes, with 1,188 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR2C1-associated genes across cancer lineages are COL6A5, EXOC1, and GRIK2. Each is linked with OR2C1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2C1-to-partner and partner-to-OR2C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL6A5 grouped by OR2C1-low versus OR2C1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2C1→partner) and Y-score (partner→OR2C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	COL6A5 →	+2.146	+3.860	.007	.007	1	3
LUNG_NSCLC_LUAD	EXOC1 →	+4.772	+5.339	.004	.004	1	3
LARGE_INTESTINE	GRIK2 →	+1.836	+2.906	.009	.009	1	3
LUNG_NSCLC_LUAD	DOK5 →	+4.187	+5.000	.008	.008	1	2
LUNG_NSCLC_LUAD	SMAP1 →	+5.772	+5.772	.002	.002	1	2
LUNG_NSCLC_LUAD	FBRSL1 →	+4.187	+5.000	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,188 associations by consensus.

COL6A5 by OR2C1 expression — SKIN

Explore this box plot interactively →