OR2B6

Across TCGA patient cohorts, OR2B6 mutation is significantly associated with the RNA expression of many other genes, with 1,853 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR2B6-associated genes across cancer lineages are RNA5SP73, RNU6-352P, and ITGB1P1. Each is linked with OR2B6 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2B6-to-partner and partner-to-OR2B6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP73 grouped by OR2B6-low versus OR2B6-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2B6→partner) and Y-score (partner→OR2B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP73 →	+0.553	+3.652	<.001	.009	3	3
BRCA	RNU6-352P →	+0.219	+7.731	.008	.009	3	2
SKCM	ITGB1P1 →	+0.465	+2.341	.008	.003	3	2
SKCM	DCP1A →	+0.516	+3.610	.003	.001	3	2
UCEC	CWC25 →	+0.480	+3.491	.007	.002	3	2
BLCA	RN7SL188P →	+0.178	+6.444	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,853 associations by consensus.

RNA5SP73 by OR2B6 expression — LUSC

Explore this box plot interactively →