OR2B6

Across TCGA pan-cancer cohorts, OR2B6 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated OR2B6 data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher OR2B6 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR2B6 expression acts as an unfavorable survival marker, although some lineages such as BLCA and OV show a favorable association.

KIRC, ACC, and COAD are the cancer types where OR2B6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.526	0.726	<.001	160	view →
ACC	OS	Median	All	0.764	0.974	<.001	103	view →
COAD	OS	Tertile	III,IV	0.369	0.712	.002	66	view →
LIHC	DFS	Tertile	All	0.461	0.665	.001	50	view →
KIRP	DFS	Median	All	0.488	0.762	<.001	49	view →
LGG	OS	Median	All	0.379	0.518	<.001	48	view →
UCEC	DFS	Median	All	0.544	0.766	<.001	38	view →
LUAD	DFS	Tertile	All	0.605	0.727	.007	37	view →
KICH	DFS	Quartile	All	0.608	1.000	.005	36	view →
BLCA	OS	Tertile	All	0.693	0.298	.002	34	view →
OV	DFS	Tertile	IV	0.624	0.302	.003	34	view →
CESC	OS	Tertile	II,III,IV	0.757	0.344	.002	30	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

OR2B6–KIRC (DFS)

Open the KIRC breakdown →