Across TCGA patient cohorts, OR2A42 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2A42-associated genes across cancer lineages are Shc_pY317, VHL, and C-Raf. Each is linked with OR2A42 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2A42-to-partner and partner-to-OR2A42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A42→partner) and Y-score (partner→OR2A42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.212	-3.000	.015	.037	3	2
UCEC	VHL →	-1.198	-3.000	.002	.036	3	1
UCEC	C-Raf →	+0.221	+3.000	.007	.037	2	1
UCEC	EGFR_pY1068 →	-0.320	-3.000	.027	.037	1	1
UCEC	Cyclin-B1 →	+0.730	+3.000	.024	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

OR2A42 survival (RNA) · tumor vs normal (RNA) · all OR2A42 data types