OR2A4

Across TCGA patient cohorts, OR2A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,818 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR2A4-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Methylation, and Positive regulation of DNA repair. Each is linked with OR2A4 in more than 16 cancer types. Because this analysis shows association rather than direction, both OR2A4-to-partner and partner-to-OR2A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by OR2A4-low versus OR2A4-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A4→partner) and Y-score (partner→OR2A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of double-strand break repair →	+0.091	+0.035	.002	.009	1	17
STAD	Methylation →	+0.047	+0.086	<.001	<.001	3	14
ESCA	Positive regulation of DNA repair →	+0.051	+0.105	.002	<.001	3	14
ESCA	Regulation of double-strand break repair →	+0.049	+0.080	.005	.001	2	14
ESCA	Positive regulation of DNA metabolic process →	+0.056	+0.109	.002	<.001	3	13
STAD	Facultative heterochromatin formation →	+0.049	+0.073	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,818 associations by consensus.

Positive regulation of double-strand break repair by OR2A4 expression — SCLC

Explore this box plot interactively →