OR2A4

Across TCGA cell cohorts, OR2A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,430 significant associations in total. BONE shows the largest number of these associations.

The most reproducible OR2A4-associated GO terms across cancer lineages are Basophil activation, Actin filament severing, and Barbed-end actin filament capping. Each is linked with OR2A4 in more than 4 cancer types. Because this analysis shows association rather than direction, both OR2A4-to-partner and partner-to-OR2A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophil activation grouped by OR2A4-low versus OR2A4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A4→partner) and Y-score (partner→OR2A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Basophil activation →	-0.262	-0.639	<.001	<.001	3	5
BONE	Actin filament severing →	-0.154	-0.485	<.001	.006	3	4
BONE	Barbed-end actin filament capping →	-0.246	-0.546	<.001	.002	3	4
BREAST	Xenobiotic detoxification by transmembrane export across the plasma membrane →	+0.117	+0.069	.001	.003	3	3
BONE	Regulation of heart rate by chemical signal →	-0.460	-0.596	<.001	<.001	3	3
BREAST	Negative regulation of protein modification process →	-0.042	-0.088	.005	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,430 associations by consensus.

Basophil activation by OR2A4 expression — BONE

Explore this box plot interactively →