Across TCGA patient cohorts, OR2A2 mutation is significantly associated with the RNA expression of many other genes, with 1,309 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2A2-associated genes across cancer lineages are ITGB1BP1, CEP55, and PSMB3. Each is linked with OR2A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2A2-to-partner and partner-to-OR2A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A2→partner) and Y-score (partner→OR2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ITGB1BP1 →	+0.569	+1.970	<.001	<.001	3	3
SKCM	CEP55 →	+0.545	+1.999	.005	.009	3	3
SKCM	PSMB3 →	+0.298	+2.191	.001	.008	3	2
LUAD	ZNF787 →	+0.521	+3.404	.009	.004	3	2
LUAD	H2AX →	+0.795	+3.333	.001	.005	3	2
LUAD	RNU6-922P →	+0.340	+3.471	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,309 associations by consensus.

Exploration

OR2A2 survival (RNA) · tumor vs normal (RNA) · all OR2A2 data types