Across TCGA pan-cancer cohorts, OR2A2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR2A2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where OR2A2 RNA is repressed in tumor relative to normal tissue. In most cancer types OR2A2 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA and BRCA are the cancer types where OR2A2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR2A2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.052	.005	6	view →
BRCA	All	III,IV	−0.041	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: OR2A2 RNA expression & survival · all OR2A2 data types