Across TCGA cell cohorts, OR2A2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR2A2-associated genes across cancer lineages are IL1F10, OR8G5, and MINAR2. Each is linked with OR2A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2A2-to-partner and partner-to-OR2A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A2→partner) and Y-score (partner→OR2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	IL1F10 →	+0.127	+3.695	.003	.003	3	1
LUNG_NSCLC_LUAD	OR8G5 →	+0.405	+2.882	.002	.009	3	1
LARGE_INTESTINE	MINAR2 →	+0.027	+3.204	.001	<.001	3	1
LARGE_INTESTINE	BCAS2 →	+0.622	+3.064	.001	.009	2	1
LARGE_INTESTINE	GRIK4 →	+0.398	+3.273	.005	.006	2	1
LARGE_INTESTINE	FAM153B →	+0.456	+2.426	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

OR2A2 survival (RNA) · tumor vs normal (RNA) · all OR2A2 data types